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Integrin beta 3 抗体 (Alexa Fluor 647)

This anti-Integrin beta 3 antibody is a 仓鼠 单克隆 antibody detecting Integrin beta 3 in WB, IHC 和 FACS. Suitable for 小鼠 和 大鼠.
产品编号 ABIN2657831
发货至: 中国

Quick Overview for Integrin beta 3 抗体 (Alexa Fluor 647) (ABIN2657831)

抗原

See all Integrin beta 3 (ITGB3) 抗体
Integrin beta 3 (ITGB3)

适用

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小鼠, 大鼠

宿主

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仓鼠

克隆类型

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单克隆

标记

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This Integrin beta 3 antibody is conjugated to Alexa Fluor 647

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

克隆位点

2C9-G2 (HMbeta3-1)
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原

    Integrin beta 3 (ITGB3)

    别名

    CD61

    背景

    CD61 is a 110 kD integrin β chain also known as β3 integrin or gpIIIa. It associates with the integrin αv chain (CD51) to form the vitronectin receptor. In addition, CD61 can associate with the integrin αIIb chain (CD41) to form the gpIIb/IIIa complex. CD61 is expressed on platelets, megakaryocytes, endothelium, smooth muscle, a subset of B cells, myeloid cells, osteoclasts, and mast cells. CD61, in conjunction with CD41 or CD51, mediates adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. Leukocyte-endothelial adhesion is mediated by the binding of αv/β3 integrin or vitronectin receptor to CD31 (PECAM-1).

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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