L-Selectin 抗体 (Alexa Fluor 488)
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- 抗原 See all L-Selectin (SELL) 抗体
- L-Selectin (SELL) (Selectin L (SELL))
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适用
- 化学剂
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This L-Selectin antibody is conjugated to Alexa Fluor 488
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应用范围
- Flow Cytometry (FACS)
- 交叉反应
- Chimpanzee, 牛
- 纯化方法
- The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.
- 克隆位点
- DREG-56
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product SELL Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C
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- 抗原
- L-Selectin (SELL) (Selectin L (SELL))
- 别名
- CD62L (SELL 产品)
- 物质类
- Chemical
- 背景
- CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naive lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.
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