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CD25 抗体 (Alexa Fluor 488)

This anti-CD25 antibody is a 小鼠 单克隆 antibody detecting CD25 in FACS, IHC 和 ELISA (Detection). Suitable for 大鼠.
产品编号 ABIN2657370
发货至: 中国

Quick Overview for CD25 抗体 (Alexa Fluor 488) (ABIN2657370)

抗原

See all CD25 (IL2RA) 抗体
CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

适用

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大鼠

宿主

  • 168
  • 95
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小鼠

克隆类型

  • 279
  • 73
  • 4
单克隆

标记

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This CD25 antibody is conjugated to Alexa Fluor 488

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA (Detection)

克隆位点

OX-39
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原

    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

    别名

    CD25

    背景

    CD25 is a 55 kD glycoprotein also known as IL-2 receptor α chain. It is broadly expressed on activated T and B cells, a subset of thymic and splenic dendritic cells, and intestinal epithelial cells in the rat. IL-2 is a critical cytokine involved in lymphocyte proliferation and clonal expansion. IL-2 signaling requires the high affinity IL-2 receptor composed of IL-2 receptor chains α, β, and γ. The OX-39 antibody weakly inhibits IL-2 binding to the IL-2 receptor and has been shown to block some IL-2 mediated responses in vitro.

    途径

    JAK/STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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