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CCR3 抗体 (Alexa Fluor 647)

This Alexa Fluor 647-conjugated 大鼠 单克隆 anti-CCR3 antibody (Clone J073E5) specifically detects CCR3 in WB, FACS 和 IHC. The antibody is reactive with 小鼠 samples.
产品编号 ABIN2657147
发货至: 中国
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北京 101111
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Quick Overview for CCR3 抗体 (Alexa Fluor 647) (ABIN2657147)

抗原

See all CCR3 抗体
CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CCR3 antibody is conjugated to Alexa Fluor 647

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC)

克隆位点

J073E5
  • 纯化方法

    The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原

    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

    别名

    CD193

    背景

    CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-α receptor like-2, and eotaxin receptor, is a member of the G protein-coupled, seven transmembrane receptor family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CD193 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CD193 is expressed on mouse eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, hematopoietic progenitor cells, and keratinocytes. It is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CD193 also function as a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CD193 has been shown to inhibit HIV infection in some cell types.
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