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- 抗原 See all CCR2 抗体
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CCR2 antibody is conjugated to APC
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应用范围
- Western Blotting (WB), ELISA, Functional Studies (Func), Immunoprecipitation (IP)
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
- 克隆位点
- K036C2
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product CCR2 Primary Antibody
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anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody
CCR2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibodyCCR2 适用: 人 WB, ELISA, FACS, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 3B6B1 unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibodyCCR2 适用: 人, 小鼠, 大鼠, 犬 IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 301-373) antibodyCCR2 适用: 人, 小鼠, 大鼠 ELISA, FACS, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) (N-Term) antibodyCCR2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody (Biotin)CCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal Biotin
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody (PE)CCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal PE
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody (PerCP)CCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal PerCP
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody (APC)CCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal APC
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody (Atto 488)CCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal Atto 488
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C
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- 抗原
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
- 别名
- CD192 (CCR2 产品)
- 别名
- CC-CKR-2 antibody, CCR-2 antibody, CCR2A antibody, CCR2B antibody, CD192 antibody, CKR2 antibody, CKR2A antibody, CKR2B antibody, CMKBR2 antibody, MCP-1-R antibody, ACKR5 antibody, CKRX antibody, CRAM antibody, CRAM-A antibody, CRAM-B antibody, HCR antibody, Cc-ckr-2 antibody, Ccr2a antibody, Ccr2b antibody, Ckr2 antibody, Ckr2a antibody, Ckr2b antibody, Cmkbr2 antibody, mJe-r antibody, C-C motif chemokine receptor 2 antibody, C-C motif chemokine receptor like 2 antibody, chemokine (C-C motif) receptor 2 antibody, CCR2 antibody, CCRL2 antibody, Ccr2 antibody, LOC484790 antibody
- 背景
- CCR2 is a chemokine receptor that binds monocyte chemoattractant proteins (MCP-1, 2, 3 and 4). Two spliced variants were initially described for CCR2 (CCR2A and CCR2B). These variants differ in their terminal carboxyl tails. Monocyte adhesion to the arterial endothelium and subsequent migration into the intima are central events in the pathogenesis of atherosclerosis. CCR2 and MCP-1 have been associated to atherosclerotic plaques. MCP-1 is induced by modified-LDL in endothelial cells and may trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Local overexpression of MCP-1 at vessel walls induces infiltration of macrophages and formation of atherosclerotic lesions. Obesity induces an inflammatory state that is implicated in many clinically important complications, including insulin resistance, diabetes, atherosclerosis, and non-alcoholic fatty liver disease. CCR2 influences the development of obesity and associated adipose tissue inflammation.
- 途径
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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