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IL-6 Receptor 抗体 (APC)

IL6R 适用: 大鼠, 小鼠 ICFC 宿主: 大鼠 Monoclonal D7715A7 APC
产品编号 ABIN2656903
发货至: 中国
  • 抗原 See all IL-6 Receptor (IL6R) 抗体
    IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
    适用
    • 49
    • 19
    • 16
    大鼠, 小鼠
    宿主
    • 47
    • 22
    • 5
    • 1
    • 1
    大鼠
    克隆类型
    • 50
    • 25
    • 1
    单克隆
    标记
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    • 5
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    This IL-6 Receptor antibody is conjugated to APC
    应用范围
    • 51
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    Intracellular Flow Cytometry (ICFC)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
    克隆位点
    D7715A7
    亚型
    IgG2b kappa
    Top Product
    Discover our top product IL6R Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C
  • 抗原
    IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
    别名
    CD126 (IL6R 产品)
    别名
    IL6R antibody, il-6ra antibody, CD126 antibody, IL-6R-1 antibody, IL-6RA antibody, IL6Q antibody, IL6RA antibody, IL6RQ antibody, gp80 antibody, IL6R1 antibody, Il6ra antibody, IL-6Ralpha antibody, IL-6R antibody, Il6r antibody, interleukin 6 receptor antibody, interleukin 6 receptor, alpha antibody, IL6R antibody, il6r antibody, Il6r antibody, Il6ra antibody
    背景
    CD126 is an 80 kD IL-6 receptor α chain also known as IL-6R. It is a member of the immunoglobulin superfamily that is expressed on activated T and B cells, monocytes, hepatocytes, and plasma cells. High affinity IL-6 receptors are formed by the non-covalent association of CD126 and the IL-6 receptor β chain (CD130 or gp130). CD126 binds IL-6 with low affinity, but does not signal. The β chain (gp130, CD130) does not bind IL-6 by itself, but associates with the α-chain/IL-6 complex to initiate signal transduction. IL-6 binding to the receptor complex results in the stimulation of B and T cells, and hematopoietic precursor proliferation and differentiation. The D7715A7 (15A7) antibody blocks IL-6/IL-6 receptor interactions.
    途径
    JAK/STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
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