HDAC2 抗体
Quick Overview for HDAC2 抗体 (ABIN265455)
抗原
See all HDAC2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of HDAC2 protein. (region surrounding Asp388)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Histone Deacetylase 2 (HDAC2) (AA 456-488), (C-Term) antibody
HDAC2 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB5718 unconjugated
anti-Histone Deacetylase 2 (HDAC2) antibodyHDAC2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Histone Deacetylase 2 (HDAC2) antibodyHDAC2 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 3B7 unconjugated
anti-Histone Deacetylase 2 (HDAC2) (AA 410-439) antibodyHDAC2 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 2 (HDAC2) antibodyHDAC2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 9H4 unconjugated Recombinant Antibody
anti-Histone Deacetylase 2 (HDAC2) (pSer394) antibodyHDAC2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 2 (HDAC2) (Internal Region) antibodyVerified HDAC2 适用: 人, 小鼠 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Histone Deacetylase 2 (HDAC2) (pSer394) antibodyHDAC2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 2 (HDAC2) (AA 410-439) antibodyHDAC2 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB24526 unconjugated
anti-Histone Deacetylase 2 (HDAC2) (pSer394) antibodyHDAC2 适用: 人, 小鼠 ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 5000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- HDAC2 (Histone Deacetylase 2 (HDAC2))
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别名
- HDAC2
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背景
- In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (for p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated mammalian RPD3) and HDAC3, all of which are related to the yeast transcriptional regulator Rpd3p, have been identified as histone deacetylases.Synonyms: HD2, Histone deacetylase 2
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分子量
- approx. 60 kDa
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基因ID
- 3066
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NCBI登录号
- NP_001518
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UniProt
- Q92769
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途径
- Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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