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GANP 抗体

MCM3AP 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265431
发货至: 中国
  • 抗原 See all GANP (MCM3AP) 抗体
    GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))
    适用
    • 42
    • 14
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 40
    • 2
    克隆类型
    • 40
    • 2
    多克隆
    标记
    • 17
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This GANP antibody is un-conjugated
    应用范围
    • 29
    • 15
    • 13
    • 13
    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of GANP/MCM3AP protein. (region surrounding Glu1872)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product MCM3AP Primary Antibody
  • 应用备注
    ELISA: 1: 5000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))
    别名
    MCM3AP (MCM3AP 产品)
    别名
    GANP antibody, MAP80 antibody, SAC3 antibody, mKIAA0572 antibody, minichromosome maintenance complex component 3 associated protein antibody, germinal-center associated nuclear protein antibody, Mcm3ap antibody, MCM3AP antibody, mcm3ap antibody, LOC100026233 antibody
    背景
    Minichromosome maintenance protein 3 (MCM3) is a protein essential for the initiation of DNA replication. MCM3-associated protein (MCM3AP), also known as GANP or MAP80, is a 1980 amino acid protein which binds to MCM3. MCM3AP is an acetyltransferase that acetylates MCM3, thereby playing an indirect role in DNA replication. MCM3AP is also believed to be involved in the nuclear localization of MCM3. Localized to the nucleus and the cytoplasm, GANP (MCM3AP) is thought to have phosphorylation-dependent DNA-primase activity that is up-regulated in germinal center regions. MCM3AP contains a nuclear localization signal, a coiled-coil structure and four LXXLL motifs.Synonyms: GANP, KIAA0572, MAP80, MCM3 minichromosome maintenance deficient 3 associated protein
    分子量
    approx. 218 kDa
    基因ID
    8888
    NCBI登录号
    NP_003897
    UniProt
    O60318
    途径
    Protein targeting to Nucleus
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