FANCD2 抗体
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- 抗原 See all FANCD2 抗体
- FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FANCD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of FANCD2 protein (region surrounding Pro216).
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product FANCD2 Primary Antibody
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anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (N-Term) antibody
FANCD2 适用: 人 WB, IHC, IF, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (N-Term) antibodyFANCD2 适用: 人, 小鼠 WB, IHC, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (AA 1-230) antibodyFANCD2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (N-Term) antibodyFANCD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (pSer222) antibodyFANCD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (pSer222) antibodyFANCD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (AA 1-291) antibodyFANCD2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) antibodyFANCD2 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) antibodyFANCD2 WB, IP, ChIP 宿主: 小鼠 Monoclonal FI-17 unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) antibodyFANCD2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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- 应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))
- 别名
- FANCD2 (FANCD2 产品)
- 别名
- FANCD2 antibody, CG17269 antibody, CG31192 antibody, CG31194 antibody, Dmel\\CG17269 antibody, dmFANCD2 antibody, xfancd2 antibody, FA-D2 antibody, FA4 antibody, FACD antibody, FAD antibody, FAD2 antibody, FANCD antibody, 2410150O07Rik antibody, AU015151 antibody, BB137857 antibody, Fanconi anemia complementation group D2 antibody, CG17269 gene product from transcript CG17269-RA antibody, Fanconi anemia group D2 protein antibody, Fanconi anemia, complementation group D2 antibody, Fanconi anemia complementation group D2 L homeolog antibody, FANCD2 antibody, Fancd2 antibody, LOC100455970 antibody, fancd2 antibody, fancd2.L antibody
- 背景
- The Fanconi anemia (FA) proteins lack sequence homologies or motifs that could point to a molecular function. Phosphorylation of FANC(Fanconi anemia complementation group) proteins are thought to be important for the function of the FA pathway. Several FA proteins, including FANCA, FANCC, FANCF, and FANCG, interact in a nuclear complex, and this complex is required for the activation (monoubiquitination) of the downstream FANCD2 protein. When monoubiquitinated, the FANCD2 protein co-localizes with the breast cancer susceptibility protein BRCA1 in DNA damage induced foci. In male meiosis, FANCD2 also co-localizes with BRCA1 at synaptonemal complexes. The human FANCD2 gene maps to chromosome 3p25.3, contains 44 exons and encodes a 1,451 amino acid nuclear protein that exists as two protein isoforms.Synonyms: FACD, FACD2, Fanconi anemia group D2 protein
- 分子量
- approx. 166 kDa
- 基因ID
- 2177
- NCBI登录号
- NP_001018125
- UniProt
- Q9BXW9
- 途径
- DNA Damage Repair
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