POLB 抗体
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北京 101111
Quick Overview for POLB 抗体 (ABIN265385)
抗原
See all POLB 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of DNA polymerase beta / DPOLB protein (region surrounding Gln324).
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Polymerase (DNA Directed), beta (POLB) (AA 1-335) antibody
POLB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), beta (POLB) (AA 1-335) antibodyPOLB 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase (DNA Directed), beta (POLB) (C-Term) antibodyPOLB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), beta (POLB) antibodyKD Validated POLB 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB1475 unconjugated Recombinant Antibody
anti-Polymerase (DNA Directed), beta (POLB) (AA 1-300) antibodyPOLB 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), beta (POLB) antibodyPOLB 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Polymerase (DNA Directed), beta (POLB) (AA 55-160) antibodyPOLB 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), beta (POLB) (C-Term) antibodyPOLB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), beta (POLB) (C-Term) antibodyPOLB 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), beta (POLB) (C-Term) antibodyPOLB 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- POLB (Polymerase (DNA Directed), beta (POLB))
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别名
- DNA Polymerase beta
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背景
- DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases. DNA pol α, β, δ and ε are involved in DNA replication and repair. DNA pol δ and DNA pol ε are multisubunit enzymes, with DNA pol δ consisting of two subunits-p125, which interacts with the sliding DNA clamp protein PCNA, and p50. The nuclear-encoded DNA pol γ is the only DNA polymerase required for the replication of the mitochondrial DNA. DNA pol ζ is ubiquitously expressed in various tissues and mediates the cellular mechanism of damage-induced mutagenesis. DNA pol θ is a DNA polymerase-helicase that binds ATP and is involved in the repair of interstrand crosslinks.Synonyms: POLB
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分子量
- approx. 38 kDa
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基因ID
- 5423
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NCBI登录号
- NP_002681
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UniProt
- P06746
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途径
- DNA Damage Repair
抗原
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