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JUP 抗体

JUP 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265337
发货至: 中国
  • 抗原 See all JUP 抗体
    JUP (Junction Plakoglobin (JUP))
    适用
    • 150
    • 61
    • 53
    • 23
    • 17
    • 14
    • 13
    • 4
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 93
    • 56
    • 2
    • 1
    克隆类型
    • 84
    • 68
    多克隆
    标记
    • 68
    • 11
    • 6
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    • 4
    • 4
    • 4
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This JUP antibody is un-conjugated
    应用范围
    • 112
    • 54
    • 37
    • 36
    • 32
    • 27
    • 26
    • 22
    • 19
    • 10
    • 10
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Catenin-γ / Junction plakoglobin protein.
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product JUP Primary Antibody
  • 应用备注
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    JUP (Junction Plakoglobin (JUP))
    别名
    Junction Plakoglobin (JUP 产品)
    别名
    ARVD12 antibody, CTNNG antibody, DP3 antibody, DPIII antibody, PDGB antibody, PKGB antibody, arvd12 antibody, ctnng antibody, dp3 antibody, dpiii antibody, pdgb antibody, pkgb antibody, plak antibody, D930025P04Rik antibody, PG antibody, cb80 antibody, danPG antibody, fb11b06 antibody, jup antibody, wu:fb11b06 antibody, junction plakoglobin antibody, junction plakoglobin L homeolog antibody, Junction plakoglobin antibody, junction plakoglobin a antibody, junction plakoglobin S homeolog antibody, JUP antibody, Jup antibody, jup antibody, jup.L antibody, Tsp_06656 antibody, plak antibody, jupa antibody, jup.S antibody
    背景
    The catenins, α, β and γ, are proteins which bind to the highly conserved,intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherincomplexes play an important role mediating cellular adhesion. α-catenin was initially described as an E-cadherin associated protein, and since has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. β-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. β-catenin has also been found in complexes with the tumor suppressor protein APC. γ-catenin, also known as plakoglobin, binds with α-catenin and N-cadherin. It has been shown that the transmembrane phosphatase PTPμ associates with catenin/cadherin complexes and may regulate complex signaling.Synonyms: CTNNG, Catenin gamma, DP3, Desmoplakin III, Desmoplakin-3, JUP
    分子量
    approx. 82 kDa
    基因ID
    3728
    NCBI登录号
    NP_002221
    UniProt
    P14923
    途径
    Cell-Cell Junction Organization, Maintenance of Protein Location
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