Caspase 10 抗体
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- 抗原 See all Caspase 10 (CASP10) 抗体
- Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Caspase 10 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of Caspase 10 protein (region surrounding Lys442).
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product CASP10 Primary Antibody
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anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 223-459) antibody
CASP10 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) antibodyCASP10 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 1-110) antibodyCASP10 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E7 unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 1-110) antibodyCASP10 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 19-187) antibodyCASP10 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C9 unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) antibodyCASP10 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 220-521) antibodyCASP10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 220-236), (N-Term) antibodyCASP10 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (C-Term) antibodyCASP10 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 430-479) antibodyCASP10 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
- 别名
- Caspase-10 (CASP10 产品)
- 别名
- xCaspase-10 antibody, alps2 antibody, caspace-10 antibody, caspase-10 antibody, flice2 antibody, mch4 antibody, xCaspace-10 antibody, ALPS2 antibody, FLICE2 antibody, MCH4 antibody, caspase 10 S homeolog antibody, caspase 10 antibody, caspase-10 antibody, casp10.S antibody, casp10 antibody, CASP10 antibody, Casp10 antibody, LOC100848685 antibody
- 背景
- Four isoforms of caspase 10 (caspase 10a, 10b, 10c, and 10d) having the same prodomain but different mature large and small subdomain, have been described. Caspase 10 contains two death domains (DED) involved in linking to the death effector domain of the adapter protein FADD and recruiting the complex to TNFR1 and Fas. The inactive procaspase 10 is variably expressed in many tissues and cell lines as a cytosolic protein. The mature form of caspase 10 comprises two subunits, p23/p17 (splice isoforms) and p12. Interestingly, a caspase 9- dependent processing of caspase 10 by caspase 6 in cell-free extracts has recently been suggested. Caspase 10 can cleave and activate caspases 3, 4, 6, 7, 8, and 9. This is followed by cleavage of numerous key proteins, including the nuclear protein PARP.Synonyms: Apoptotic protease Mch-4, CASP-10, CASP10, FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE-like apoptotic protease 4, MCH4
- 分子量
- approx. 59 kDa
- 基因ID
- 843
- NCBI登录号
- NP_001193453
- UniProt
- Q92851
- 途径
- Apoptosis, Caspase Cascade in Apoptosis
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