CARD6 抗体
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- 抗原 See all CARD6 抗体
- CARD6 (Caspase Recruitment Domain Family, Member 6 (CARD6))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CARD6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of CARD6/CIN protein (region surrounding Ala2).
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product CARD6 Primary Antibody
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anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (N-Term) antibody
CARD6 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (AA 755-787) antibodyCARD6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB23118 unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (AA 666-930) antibodyCARD6 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) antibodyCARD6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (AA 1-110) antibodyCARD6 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2H8 unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (N-Term) antibodyCARD6 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (N-Term) antibodyCARD6 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (AA 1-50) antibodyCARD6 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (N-Term) antibodyCARD6 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (C-Term) antibodyCARD6 适用: 人 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- CARD6 (Caspase Recruitment Domain Family, Member 6 (CARD6))
- 别名
- CARD6 (CARD6 产品)
- 别名
- D730008L15 antibody, CARD6 antibody, CINCIN1 antibody, caspase recruitment domain family, member 6 antibody, caspase recruitment domain family member 6 antibody, Card6 antibody, CARD6 antibody
- 背景
- Membrane-associated guanylate kinase (MAGUK) family members localize to the plasma membrane and function as molecular scaffolds for the assembly of multi-protein complexes. The MAGUK family includes several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product, such as postsynaptic proteins, GKAPs, the tight junction associated proteins (ZO-1-3) and the caspase-associated recruitment domain (CARD) proteins, CARD 6, CARD 8-12 and CARD 14. CARD 6 is a 311 amino acid protein that associates with microtubules and acts as a selective mediator of NFκB activation. CARD 6 is structurally and functionally related to the superfamily of interferon (IFN)-inducible GTPases, a group that comprises host defense proteins which mediate cell-autonomous immunity. RICK, the receptorinteracting protein (RIP)-like interacting caspase-like apoptosis regulatory protein kinase, interacts with CARD 6 and targets it to aggresomes, regions of the cell where protein aggregates collect.Synonyms: Caspase recruitment domain-containing protein 6
- 分子量
- approx. 116 kDa
- 基因ID
- 84674
- NCBI登录号
- NP_115976
- UniProt
- Q9BX69
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