CARD6 抗体
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Quick Overview for CARD6 抗体 (ABIN265333)
抗原
See all CARD6 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of CARD6/CIN protein (region surrounding Ala2).
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (AA 755-787) antibody
CARD6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB23118 unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (N-Term) antibodyCARD6 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (AA 1-110) antibodyCARD6 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2H8 unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (AA 666-930) antibodyCARD6 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (N-Term) antibodyCARD6 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (AA 1-50) antibodyCARD6 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (N-Term) antibodyCARD6 适用: 人, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (N-Term) antibodyVerified CARD6 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (N-Term) antibodyCARD6 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CARD6 (Caspase Recruitment Domain Family, Member 6 (CARD6))
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别名
- CARD6
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背景
- Membrane-associated guanylate kinase (MAGUK) family members localize to the plasma membrane and function as molecular scaffolds for the assembly of multi-protein complexes. The MAGUK family includes several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product, such as postsynaptic proteins, GKAPs, the tight junction associated proteins (ZO-1-3) and the caspase-associated recruitment domain (CARD) proteins, CARD 6, CARD 8-12 and CARD 14. CARD 6 is a 311 amino acid protein that associates with microtubules and acts as a selective mediator of NFκB activation. CARD 6 is structurally and functionally related to the superfamily of interferon (IFN)-inducible GTPases, a group that comprises host defense proteins which mediate cell-autonomous immunity. RICK, the receptorinteracting protein (RIP)-like interacting caspase-like apoptosis regulatory protein kinase, interacts with CARD 6 and targets it to aggresomes, regions of the cell where protein aggregates collect.Synonyms: Caspase recruitment domain-containing protein 6
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分子量
- approx. 116 kDa
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基因ID
- 84674
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NCBI登录号
- NP_115976
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UniProt
- Q9BX69
抗原
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