ASK1 抗体
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- 抗原 See all ASK1 (MAP3K5) 抗体
- ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ASK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects endogenous levels of MEKK5 / ASK1 protein(region surrounding Glu960).
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product MAP3K5 Primary Antibody
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (pThr845) antibody
MAP3K5 适用: 人, 小鼠, 大鼠, Cow WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) antibodyMAP3K5 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2-00E-04 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (AA 1231-1374) antibodyMAP3K5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (pSer966) antibodyMAP3K5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (AA 693-933) antibodyMAP3K5 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (AA 821-849) antibodyMAP3K5 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB12839 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (AA 1231-1374) antibodyMAP3K5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E3 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (N-Term) antibodyMAP3K5 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (pSer83) antibodyMAP3K5 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (C-Term) antibodyMAP3K5 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/20000approx. 1/40000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
- 别名
- MEKK5 / ASK1 (MAP3K5 产品)
- 别名
- ASK1 antibody, MAPKKK5 antibody, MEKK5 antibody, mitogen-activated protein kinase kinase kinase 5 antibody, MUD21.11 antibody, MUD21_11 antibody, 7420452D20Rik antibody, ASK antibody, Mekk5 antibody, Ask1 antibody, RGD1306565 antibody, mitogen-activated protein kinase kinase kinase 5 antibody, MAP3K5 antibody, MAPKKK5 antibody, Map3k5 antibody, map3k5 antibody
- 背景
- Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli including growth factors. The MEK kinases (also called MAP kinase kinase kinases) phosphorylate and activate the MAP kinases, including ERK, JNK and p38. The MEK kinases characterized to date include Raf-1, Raf-B, MOS, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4 and ASK 1 (also designated MEK kinase-5). MEK kinase-1 has been shown to phosphorylate MEK-1 via a Raf-independent pathway. Evidence suggests that MEK-3 is preferentially activated by MEK kinase-3 and that MEK-4 is activated by both MEK kinase-2 and MEK kinase-3. MEK kinase-4 has been shown to specifically activate the JNK pathway. ASK1 activates both MEK-4 and MEK-3/MEK-6 pathways.Synonyms: Apoptosis signal-regulating kinase 1, MAP3K5, MAPK/ERK kinase kinase 5, MAPKKK5, Mitogen-activated protein kinase kinase kinase 5
- 分子量
- approx. 155 kDa
- 基因ID
- 4217
- NCBI登录号
- NP_005914
- UniProt
- Q99683
- 途径
- MAPK Pathway, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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