TP53I3 抗体
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北京 101111
Quick Overview for TP53I3 抗体 (ABIN265005)
抗原
See all TP53I3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects recombinant PIG-3 protein by Western blot.
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纯化方法
- Purified
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免疫原
- Antibody developed using full-length recombinant PIG-3 protein.
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亚型
- IgG
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anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 1-332) antibody
TP53I3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 163-332) antibodyTP53I3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) antibodyTP53I3 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 1-332) antibodyTP53I3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 1-332) antibodyTP53I3 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal AT1C9 unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 1-332) antibodyTP53I3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 1-332) antibodyTP53I3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal AT1C9 unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (C-Term) antibodyTP53I3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) antibodyTP53I3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) antibodyTP53I3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal AT1C9 unconjugated
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应用备注
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Western Blot:
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS, 0.08 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))
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别名
- TP53I3
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背景
- P53 inducible gene-3 (PIG-3) may be a long-lived reporter, which may be useful for detecting transient activation of p53. The p53 tumor suppressor is the most commonly mutated gene in human cancers. The p53 protein, which is stabilized in response to different biological checkpoints, is activated by DNA damage, hypoxia, viral infection, or oncogene activation resulting in efects such as cell cycle arrest, apoptosis, senescence, differentiation, and antiangiogenesis. Other genes also implicated in the downstream effects as a result of p53 activation are: p21WAF1, GADD45, 14-3-3, bax, Fas/APO1, KILLER/ DR5, Tsp1, IGF-BP3 and others. The p53-inducible gene 3 (PIG3), was recently identified in a screen for genes induced by p53 before the onset of apoptosis. PIG3 shares significant homology with the oxidoreductases from several species. PIG3 protein is localized to the cytoplasm and induced in primary, non-transformed, and transformed cell cultures after exposure to genotoxic agents. The induction of PIG3 by p53 occurrs with delayed kinetics as compared with other p53 downstream targets, such as p21 and MDM2. PIG3 levels are increased during p53-mediated growth arrest. Elevated levels of PIG3 are maintained in cells that resume cycling in the absence of ectopic p53 expression.Synonyms: PIG3, Quinone oxidoreductase PIG3, Tumor protein p53-inducible protein 3, p53-induced gene 3 protein
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基因ID
- 9540
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NCBI登录号
- NP_001193731
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UniProt
- Q53FA7
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途径
- p53 Pathway
抗原
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