ADAM10 抗体 (AA 732-748)
Quick Overview for ADAM10 抗体 (AA 732-748) (ABIN264988)
抗原
See all ADAM10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 732-748
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特异性
- This antibody recognizes ADAM10.
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纯化方法
- Purified
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免疫原
- Synthetic peptide corresponding to amino acids 732-748 off the Human ADAM10.
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亚型
- IgG
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anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 420-641) antibody
ADAM10 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 10 (ADAM10) antibodyADAM10 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6C3C7 unconjugated
anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 400-414), (Extracellular) antibodyADAM10 适用: 小鼠 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 501-600) antibodyADAM10 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 10 (ADAM10) antibodyADAM10 适用: 人 WB, FACS, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal 11G2 unconjugated
anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 732-748) antibodyADAM10 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 10 (ADAM10) antibody (PE)ADAM10 适用: 人 FACS 宿主: 小鼠 Monoclonal 11G2 PE
anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 214-500) antibodyADAM10 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 10 (ADAM10) antibodyADAM10 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 10 (ADAM10) (AA 218-445) antibodyADAM10 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 0.25-1 μg/mL. Detects an 85 kDa band can be detected in Jurkat cell lysates which may representprecursor protein. A faint 60 kDa band is also detected in some cell lines, including Jurkat,which may be processed mature protein. Positive Control/Tissue Expression: Jurkat whole cell lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate buffered saline solution containing 0.02 % Sodium Azide as a preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C.
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- ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
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别名
- CD156c / ADAM10
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背景
- Proinflammatory cytokine tumor necrosis factor-a (TNF-a) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-a, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-a, notch and its ligand delta (1-3). The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively, (1,2,4). ADAM10 mRNA is expressed in a variety of human and bovine tissues (1,4).Synonyms: Disintegrin and metalloproteinase domain-containing protein 10, KUZ, Kuzbanian protein homolog, MADM, Mammalian disintegrin-metalloprotease
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基因ID
- 102
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NCBI登录号
- NP_001101
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UniProt
- O14672
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途径
- Notch Signaling, EGFR Signaling Pathway
抗原
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