(7 references)-
- 抗原 See all S1PR1 抗体
- S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This S1PR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody reacts to EDG1.
- 纯化方法
- Purified
- 免疫原
- Synthetic peptide derived from the C-terminal of the EDG-1 receptor
- 亚型
- IgG
- Top Product
- Discover our top product S1PR1 Primary Antibody
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anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (C-Term) antibody
S1PR1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 51-150) antibodyS1PR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 311-382) antibodyS1PR1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 1-47) antibodyS1PR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E12 unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) antibodyS1PR1 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 1E3H5 unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 1-47) antibodyS1PR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F11 unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (N-Term) antibodyS1PR1 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (Internal Region) antibodyS1PR1 适用: 人, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (Ser311) antibodyS1PR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 1-382) antibodyS1PR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 5-10 μg/mL, Detects an approximately 44 kDa band in RH7777 cellstransfected with full length human EDG-1. Due to low expression of EDG receptors, werecommend use of Pierce Femto Signal substrate for western blot development.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- Phosphate buffered saline with 0.08 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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: "A short linear motif in BNIP3L (NIX) mediates mitochondrial clearance in reticulocytes." in: Autophagy, Vol. 8, Issue 9, pp. 1325-32, (2013) (PubMed).
: "The S1P2 receptor negatively regulates platelet-derived growth factor-induced motility and proliferation." in: Molecular and cellular biology, Vol. 25, Issue 10, pp. 4237-49, (2005) (PubMed).
: "Sphingosine 1-phosphate activates Weibel-Palade body exocytosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 31, pp. 11483-7, (2004) (PubMed).
: "Differential transactivation of sphingosine-1-phosphate receptors modulates NGF-induced neurite extension." in: The Journal of cell biology, Vol. 166, Issue 3, pp. 381-92, (2004) (PubMed).
: "Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and haematogenous metastasis of melanoma cells." in: The Biochemical journal, Vol. 374, Issue Pt 3, pp. 715-22, (2003) (PubMed).
: "Phospholipase D activation by sphingosine 1-phosphate regulates interleukin-8 secretion in human bronchial epithelial cells." in: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 30227-35, (2002) (PubMed).
: "Activation-regulated expression and chemotactic function of sphingosine 1-phosphate receptors in mouse splenic T cells." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 16, Issue 14, pp. 1874-8, (2002) (PubMed).
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: "A short linear motif in BNIP3L (NIX) mediates mitochondrial clearance in reticulocytes." in: Autophagy, Vol. 8, Issue 9, pp. 1325-32, (2013) (PubMed).
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- 抗原
- S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
- 别名
- EDG-1 / S1PR1 (S1PR1 产品)
- 别名
- CD363 antibody, CHEDG1 antibody, D1S3362 antibody, ECGF1 antibody, EDG-1 antibody, EDG1 antibody, S1P1 antibody, AI849002 antibody, Edg1 antibody, Lpb1 antibody, S1p antibody, S1p1 antibody, S1P receptor 1 antibody, S1P receptor Edg-1 antibody, edg1 antibody, etID43307.22 antibody, s1p1 antibody, wu:fb98f05 antibody, s1pr1 antibody, xts1p1 antibody, sphingosine-1-phosphate receptor 1 antibody, sphingosine-1-phosphate receptor 1 L homeolog antibody, S1PR1 antibody, S1pr1 antibody, s1pr1 antibody, s1pr1.L antibody
- 背景
- EDG-1 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-1 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-1 is expressed in cardiovascular, leukocytecontaining and other tissues.Synonyms: CHEDG1, D1S3362, ECGF1, EDG1, Endothelial differentiation G-protein coupled receptor 1, FLJ58121, S1P receptor 1, S1PR1, Sphingosine 1-phosphate receptor 1
- 基因ID
- 1901
- NCBI登录号
- NP_001391
- UniProt
- P21453
- 途径
- Signaling Events mediated by VEGFR1 and VEGFR2
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