TP53I3 抗体
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北京 101111
Quick Overview for TP53I3 抗体 (ABIN264400)
抗原
See all TP53I3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes PIG3 (p53 inducible gene 3).
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产品特性
- Synonyms: p53-induced gene 3 protein, PIG3, Tumor protein p53-inducible protein 3, Quinoneoxidoreductase PIG3
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纯化方法
- Purified
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免疫原
- Hybridoma produced by the fusion of splenocytes from mice immunized with recombinanthuman PIG-3 protein. Genename: TP53I3
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亚型
- IgG1
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anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 1-332) antibody
TP53I3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 163-332) antibodyTP53I3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) antibodyTP53I3 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 1-332) antibodyTP53I3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 1-332) antibodyTP53I3 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal AT1C9 unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 1-332) antibodyTP53I3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 1-332) antibodyTP53I3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal AT1C9 unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) (C-Term) antibodyTP53I3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) antibodyTP53I3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Protein 3 (TP53I3) antibodyTP53I3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal AT1C9 unconjugated
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应用备注
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Western Blot (5-10 μg/mL). Positive Control: Jurkat cell lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, 0.08 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch. -
有效期
- 12 months
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- TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))
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别名
- TP53I3
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背景
- P53 Inducible Gene-3 (PIG-3) may be a long-lived reporter, which may be useful for detecting transient activation of p53. The p53 tumor suppressor is the most commonly mutated gene in human cancers. The p53 protein, which is stabilized in response to different biological checkpoints, is activated by DNA damage, hypoxia, viral infection, or oncogene activation resulting in efects such as cell cycle arrest, apoptosis, senescence, differentiation, and antiangiogenesis. Other genes also implicated in the downstream effects as a result of p53 activation are: p21WAF1, GADD45, 14-3-3, bax, Fas/APO1, KILLER/ DR5, Tsp1, IGF-BP3 and others. The p53-inducible gene 3 (PIG3), was recently identified in a screen for genes induced by p53 before the onset of apoptosis. PIG3 shares significant homology with the oxidoreductases from several species. PIG3 protein is localized to the cytoplasm and induced in primary, non-transformed, and transformed cell cultures after exposure to genotoxic agents. The induction of PIG3 by p53 occurrs with delayed kinetics as compared with other p53 downstream targets, such as p21 and MDM2. PIG3 levels are increased during p53-mediated growth arrest. Elevated levels of PIG3 are maintained in cells that resume cycling in the absence of ectopic p53 expression.Synonyms: PIG3, Quinone oxidoreductase PIG3, Tumor protein p53-inducible protein 3, p53-induced gene 3 protein
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基因ID
- 9540
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UniProt
- Q53FA7
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途径
- p53 Pathway
抗原
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