p130 抗体 (N-Term)
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北京 101111
Quick Overview for p130 抗体 (N-Term) (ABIN264369)
抗原
See all p130 (RBL2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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特异性
- This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130 kDa.
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产品特性
- Synonyms: Retinoblastoma-like protein 2, RB2, 130 kDa retinoblastoma-associated protein, p130,Retinoblastoma-related protein 2, RBR-2, pRb2
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纯化方法
- Protein A/G chromatography.
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免疫原
- GST fusion protein to the N terminus of p130.
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亚型
- IgG1
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应用备注
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Suitable for Western Blots at 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.08 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch -
有效期
- 12 months
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- p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
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别名
- RBL2 / p130
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背景
- P130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107 (collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors.Synonyms: 130 kDa retinoblastoma-associated protein, RB2, RBR-2, Retinoblastoma-like protein 2, Retinoblastoma-related protein 2, p130, pRb2
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基因ID
- 5934
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UniProt
- Q08999
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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