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p130 抗体 (N-Term)

This anti-p130 antibody is a 小鼠 单克隆 antibody detecting p130 in WB. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN264369
发货至: 中国

Quick Overview for p130 抗体 (N-Term) (ABIN264369)

抗原

See all p130 (RBL2) 抗体
p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))

适用

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人, 大鼠, 小鼠

宿主

  • 63
  • 5
小鼠

克隆类型

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单克隆

标记

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This p130 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

KAB40
  • 抗原表位

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    N-Term

    特异性

    This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130 kDa.

    产品特性

    Synonyms: Retinoblastoma-like protein 2, RB2, 130 kDa retinoblastoma-associated protein, p130,Retinoblastoma-related protein 2, RBR-2, pRb2

    纯化方法

    Protein A/G chromatography.

    免疫原

    GST fusion protein to the N terminus of p130.

    亚型

    IgG1
  • 应用备注

    Suitable for Western Blots at 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.08 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch

    有效期

    12 months
  • 抗原

    p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))

    别名

    RBL2 / p130

    背景

    P130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107 (collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors.Synonyms: 130 kDa retinoblastoma-associated protein, RB2, RBR-2, Retinoblastoma-like protein 2, Retinoblastoma-related protein 2, p130, pRb2

    基因ID

    5934

    UniProt

    Q08999

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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