CD25 抗体 (APC)
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北京 101111
Quick Overview for CD25 抗体 (APC) (ABIN264237)
抗原
See all CD25 (IL2RA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Identification of human receptor for Interleukin-2 (IL-2R) expressing the 55,000 M.W. surface antigen. This antibody is specific for Interleukin-2 Receptor Lymphocytes.
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产品特性
- Synonyms: Interleukin-2 receptor alpha chain, IL-2 receptor alpha subunit, IL-2-RA, IL2-RA, p55, TACantigen
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亚型
- IgG1
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应用备注
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Flow Cytometry. Monitoring of activated T cells in peripheral blood. Analysis of NK subsets. Study of B cell activation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
实验流程
- PBMC: Add 10 ul of MAB/10e6 PBMC in 100 ul PBS. Mix gently and incubate for 15 minutes at 2-8°C. Wash twice with PBS and analyze or fix with 0. 5% v/v of paraformaldehyde in PBS andanalyze.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.2 % protein carrier and 0.08 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Store the antibody undiluted at 2-8 °C. Do Not Freeze!
Shelf life: One year from despatch. -
有效期
- 12 months
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- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
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别名
- CD25 / IL2RA
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背景
- The Interleukin 2 Receptor alpha and beta chains, together with the common gamma chain, constitute the high affinity IL2 receptor present on activated T and B cells, thymocyte subset, pre B cells and T regulatory cells. Homodimeric alpha chains result in low affinity receptor, while homodimeric beta chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2 Receptor alpha has been isolated and determined to result from extracellular proteolysis. Alternately spliced IL2 Receptor alpha mRNAs have been isolated, but the significance of each is presently unknown.Synonyms: IL-2 receptor alpha subunit, IL-2-RA, IL2-RA, Interleukin-2 receptor alpha chain, TAC antigen, p55
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基因ID
- 3559
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UniProt
- P01589
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途径
- JAK/STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
抗原
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