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Insulin Receptor 抗体 (AA 1353-1372)

This anti-Insulin Receptor antibody is a 兔 多克隆 antibody detecting Insulin Receptor in WB. Suitable for 人 和 猴.
产品编号 ABIN2624246
发货至: 中国

Quick Overview for Insulin Receptor 抗体 (AA 1353-1372) (ABIN2624246)

抗原

See all Insulin Receptor (INSR) 抗体
Insulin Receptor (INSR)

适用

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人, 猴

宿主

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克隆类型

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多克隆

标记

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This Insulin Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1353-1372

    特异性

    Isoform Long and isoform Short are predominantly expressed in tissue targets of insulin metabolic effects: liver, adipose tissue and skeletal muscle but are also expressed in the peripheral nerve, kidney, pulmonary alveoli, pancreatic acini, placenta vascular endothelium, fibroblasts, monocytes, granulocytes, erythrocytes and skin. Isoform Short is preferentially expressed in fetal cells such as fetal fibroblasts, muscle, liver and kidney. Found as a hybrid receptor with IGF1R in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Overexpressed in several tumors, including breast, colon, lung, ovary, and thyroid carcinomas. .

    交叉反应 (详细)

    No cross reactivity with other proteins.

    纯化方法

    Immunogen affinity purified

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Insulin Receptor(1353-1372aa RSYEEHIPYTHMNGGKKNGR), different from the related rat and mouse sequences by two amino acids.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    溶解方式

    Distilled water

    浓度

    Lot specific

    缓冲液

    Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.
  • 抗原

    Insulin Receptor (INSR)

    别名

    INSR / Insulin Receptor

    背景

    Name/Gene ID: INSR
    Subfamily: Insulin receptor
    Family: Protein Kinase

    Synonyms: INSR, CD220, ILP receptor, Insulin receptor, IR, HHF5, CD220 antigen

    基因ID

    3643

    途径

    NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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