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GDNF 抗体 (AA 142-158)

This anti-GDNF antibody is a 兔 多克隆 antibody detecting GDNF in WB, IHC, ICC 和 IHC (p). Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN2621281
发货至: 中国
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北京 101111
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GDNF 抗体 (AA 142-158) (ABIN2621281)

抗原

See all GDNF 抗体
GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))

适用

  • 83
  • 56
  • 45
  • 16
  • 16
人, 小鼠, 大鼠, 猴

宿主

  • 80
  • 8
  • 3
  • 3
  • 1

克隆类型

  • 67
  • 25
  • 2
多克隆

标记

  • 50
  • 10
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GDNF antibody is un-conjugated

应用范围

  • 80
  • 31
  • 26
  • 24
  • 13
  • 13
  • 9
  • 8
  • 5
  • 5
  • 5
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 16
    • 9
    • 8
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 142-158

    特异性

    In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change. .

    交叉反应 (详细)

    No cross reactivity with other proteins.

    纯化方法

    Immunogen affinity purified

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human GDNF(142-158aa FRYCSGSCDAAETTYDK), different from the related mouse sequence by three amino acids and rat sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    溶解方式

    Distilled water

    浓度

    Lot specific

    缓冲液

    Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.
  • 抗原

    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))

    别名

    GDNF

    背景

    Name/Gene ID: GDNF
    Family: TGF beta

    Synonyms: GDNF, HSCR3, HFB1-GDNF, ATF, HGDNF

    基因ID

    2668

    途径

    RTK signaling, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
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