BRCA1 抗体 (AA 1661-1863)
Quick Overview for BRCA1 抗体 (AA 1661-1863) (ABIN2617724)
抗原
See all BRCA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1661-1863
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特异性
- Isoform 1 and isoform 3 are widely expressed. Isoform 3 is reduced or absent in several breast and ovarian cancer cell lines.
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交叉反应 (详细)
- No cross reactivity with other proteins.
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纯化方法
- Immunogen affinity purified
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免疫原
- E.coli-derived human BRCA1 recombinant protein (Position: E1661-Y1863). Human BRCA1 shares 65% and 66% amino acid (aa) sequences identity with mouse and rat BRCA1, respectively.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Distilled water
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浓度
- Lot specific
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缓冲液
- Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg sodium azide per 100 μg antibody.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.
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- BRCA1 (Breast Cancer 1 (BRCA1))
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别名
- BRCA1
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背景
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Name/Gene ID: BRCA1
Synonyms: BRCA1, BROVCA1, BRCC1, Breast cancer 1, early onset, PPP1R53, PSCP, PNCA4, RING finger protein 53, RNF53, BRCAI, Breast cancer 1 early onset, IRIS -
基因ID
- 672
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途径
- Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus
抗原
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