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L-Selectin 抗体 (PE)

SELL 适用: 大鼠 FACS 宿主: 大鼠 Monoclonal MEL-14 PE
产品编号 ABIN2567879
发货至: 中国
  • 抗原 See all L-Selectin (SELL) 抗体
    L-Selectin (SELL) (Selectin L (SELL))
    适用
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    大鼠
    宿主
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    大鼠
    克隆类型
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    单克隆
    标记
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    This L-Selectin antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    特异性
    The MEL-14 monoclonal antibody specifically reacts with L- selectin (CD62L), a receptor with lectin-like and Epidermal Growth Factor-like domains.
    纯化方法
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    克隆位点
    MEL-14
    亚型
    IgG2a kappa
    Top Product
    Discover our top product SELL Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    储存条件
    4 °C
    储存方法
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • 抗原
    L-Selectin (SELL) (Selectin L (SELL))
    别名
    CD62L (SELL 产品)
    物质类
    Chemical
    背景
    The MEL-14 monoclonal antibody specifically reacts with L- selectin (CD62L), a receptor with lectin-like and Epidermal Growth Factor-like domains. The weight of the CD62L molecules depend on their origin: 74 kDa (on lymphocytes) or 95 kDa (on neutrophils).In the Mouseorganism, CD62L can be expressed by most thymocytes, on subsets of B and T lymphocytes, monocytes, eosinophils, and neutrophils. The L-selectin binds sulfated, fucosylated, and glycosylated glycoproteins (MadCAM-1, GLYCAM-1, and CD 34). It mediates the migration of lymphocytes to the site of inflammation and their return to the peripheral lymphoid tissues and to the HEV (high endothelial venules). In vitro, L-selectin inhibits this binding and the lymphocyte extravasation into peripheral lymph nodes.
    基因ID
    20343
    UniProt
    P18337
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