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L-Selectin 抗体

This anti-L-Selectin antibody is a 大鼠 单克隆 antibody detecting L-Selectin in FACS, IHC, IP 和 Func. Suitable for 大鼠.
产品编号 ABIN2567875
发货至: 中国

Quick Overview for L-Selectin 抗体 (ABIN2567875)

抗原

See all L-Selectin (SELL) 抗体
L-Selectin (SELL) (Selectin L (SELL))

适用

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大鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This L-Selectin antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Functional Studies (Func)

克隆位点

MEL-14
  • 特异性

    The MEL-14 monoclonal antibody specifically reacts with L- selectin (CD62L), a receptor with lectin-like and Epidermal Growth Factor-like domains.

    纯化方法

    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

    储存条件

    4 °C

    储存方法

    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • 抗原

    L-Selectin (SELL) (Selectin L (SELL))

    别名

    CD62L

    物质类

    Chemical

    背景

    The MEL-14 monoclonal antibody specifically reacts with L- selectin (CD62L), a receptor with lectin-like and Epidermal Growth Factor-like domains. The weight of the CD62L molecules depend on their origin: 74 kDa (on lymphocytes) or 95 kDa (on neutrophils).In the Mouseorganism, CD62L can be expressed by most thymocytes, on subsets of B and T lymphocytes, monocytes, eosinophils, and neutrophils. The L-selectin binds sulfated, fucosylated, and glycosylated glycoproteins (MadCAM-1, GLYCAM-1, and CD 34). It mediates the migration of lymphocytes to the site of inflammation and their return to the peripheral lymphoid tissues and to the HEV (high endothelial venules). In vitro, L-selectin inhibits this binding and the lymphocyte extravasation into peripheral lymph nodes.

    基因ID

    20343

    UniProt

    P18337
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