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CD44 抗体 (PE)

CD44 适用: 人, 小鼠 FACS 宿主: 大鼠 Monoclonal IM7 PE
产品编号 ABIN2567709
发货至: 中国
  • 抗原 See all CD44 抗体
    CD44
    适用
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    人, 小鼠
    宿主
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    大鼠
    克隆类型
    • 261
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    单克隆
    标记
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    This CD44 antibody is conjugated to PE
    应用范围
    • 277
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    Flow Cytometry (FACS)
    特异性
    The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24).
    纯化方法
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    克隆位点
    IM7
    亚型
    IgG2b kappa
    Top Product
    Discover our top product CD44 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    储存条件
    4 °C
    储存方法
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • 抗原
    CD44
    别名
    CD44 (CD44 产品)
    背景
    The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24). CD44 is expressed on hematopoietic and non-hematopoietic cells, bone marrow myeloid cells, memory T lymphocytes, periphery activated B cells, CD4+ T lymphocytes, and CD8+ T lymphocytes. The periphery B and T lymphocytes upregulate the expression of CD44. CD44 binds to hyaluronan molecules, acting as an adhesion molecule.The IM7 antibody inhibits collagen-induced arthritis in DBA/1 mice, prevents central nervous system inflammation associated with experimental autoimmune encephalomyelitis, but exacerbates the experimental autoimmune thyroiditis in CBA/J mice. The IM7 antibody also cross-reacts with dog, human, pig, horse, cat, and cow leukocytes.
    基因ID
    960, 12505
    UniProt
    P16070, P15379
    途径
    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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