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CD40 抗体

This anti-CD40 antibody is a 仓鼠 单克隆 antibody detecting CD40 in FACS 和 Func. Suitable for 小鼠 和 大鼠.
产品编号 ABIN2567688
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD40 抗体 (ABIN2567688)

抗原

See all CD40 抗体
CD40

适用

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小鼠, 大鼠

宿主

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仓鼠

克隆类型

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单克隆

标记

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This CD40 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Functional Studies (Func)

克隆位点

HM40-3
  • 特异性

    The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50.

    纯化方法

    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

    亚型

    IgM kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate-buffered aqueous solution, ph7.2.

    储存条件

    4 °C

    储存方法

    The product should be stored undiluted at 4°C. Do not freeze.
  • 抗原

    CD40

    别名

    CD40

    背景

    The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.

    基因ID

    21939

    UniProt

    P27512

    途径

    NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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