CD40 抗体 (FITC)
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- 抗原 See all CD40 抗体
- CD40
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD40 antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein.
- 纯化方法
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- 克隆位点
- 5C3
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CD40 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- 储存条件
- 4 °C
- 储存方法
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- 抗原
- CD40
- 别名
- CD40 (CD40 产品)
- 背景
- The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The 5C3 antibody partially blocks the binding of CD40L (CD154). In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation.
- 基因ID
- 958
- UniProt
- P25942
- 途径
- NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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