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CD3 epsilon 抗体 (FITC)

This anti-CD3 epsilon antibody is a 仓鼠 单克隆 antibody detecting CD3 epsilon in FACS. Suitable for 小鼠.
产品编号 ABIN2567604
发货至: 中国

Quick Overview for CD3 epsilon 抗体 (FITC) (ABIN2567604)

抗原

See all CD3 epsilon (CD3E) 抗体
CD3 epsilon (CD3E)

适用

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小鼠

宿主

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仓鼠

克隆类型

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单克隆

标记

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This CD3 epsilon antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

145-2C11
  • 特异性

    The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa ε chain of the TCR complex.

    纯化方法

    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

    储存条件

    4 °C

    储存方法

    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • 抗原

    CD3 epsilon (CD3E)

    别名

    CD3e

    背景

    The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa ε chain of the TCR complex. Together with the γ and δ subunits of CD3, the ε subunits are involved in the assembly, trafficking, and surface expression of T-cell receptor complex. CD3 is expressed on thymocytes, mature T cells, and natural killer T cells, and the ε chain enhances the antigen recognition.The 145-2C11 antibody binds to the TCR complex and, depending on the conditions, initiates T cells activation, proliferation, and apoptosis. The soluble antibody seems to block lysis of target cells by antigen-specific cytotoxic T lymphocytes. The 145-2C11 antibody does not cross-react with the rat leukocytes, and it is used as a phenotypic marker for mouse T lymphocytes.

    基因ID

    12501

    UniProt

    P22646

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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