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CD25 抗体 (APC)

IL2RA 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal PC61-5 APC
产品编号 ABIN2567382
发货至: 中国
  • 抗原 See all CD25 (IL2RA) 抗体
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    适用
    • 165
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    小鼠
    宿主
    • 137
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    大鼠
    克隆类型
    • 222
    • 70
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    单克隆
    标记
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    This CD25 antibody is conjugated to APC
    应用范围
    • 218
    • 86
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    Flow Cytometry (FACS)
    特异性
    The PC61.5 antibody specifically reacts with mouse CD25, the 55 kDa low-affinity Interleukin-2 Receptor α chain (IL-2R α), expressed on early progenitors of T and B lineage, and on B and T cells.
    纯化方法
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    克隆位点
    PC61-5
    亚型
    IgG1 lambda
    Top Product
    Discover our top product IL2RA Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    储存条件
    4 °C
    储存方法
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • 抗原
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    别名
    CD25 (IL2RA 产品)
    背景
    The PC61.5 antibody specifically reacts with mouse CD25, the 55 kDa low-affinity Interleukin-2 Receptor α chain (IL-2R α), expressed on early progenitors of T and B lineage, and on B and T cells. Together with CD122 (IL-2 Receptor β) and CD 132 (IL-2 Receptor γc, the common gamma chain), CD25 forms high-affinity receptor complexes for IL-2. Resting B and T cells and natural killer cells do not express IL-2Rα. Cd25 is also expressed on the dendritic cells, and it enhances lymphocyte differentiation and activation.The PC61.5 antibody block the binding of IL-2 to both high-affinity and low-affinity receptors.
    基因ID
    16184
    UniProt
    P01590
    途径
    JAK/STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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