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NLRP6 抗体 (AA 351-450) (Biotin)

This anti-NLRP6 antibody is a 兔 多克隆 antibody detecting NLRP6 in ELISA, IHC (fro), IHC (p) 和 IP. Suitable for 小鼠 和 大鼠.
产品编号 ABIN2559653
发货至: 中国

Quick Overview for NLRP6 抗体 (AA 351-450) (Biotin) (ABIN2559653)

抗原

See all NLRP6 抗体
NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

适用

  • 28
  • 27
  • 17
小鼠, 大鼠

宿主

  • 51
  • 1

克隆类型

  • 52
  • 1
多克隆

标记

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  • 4
  • 4
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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NLRP6 antibody is conjugated to Biotin

应用范围

  • 26
  • 25
  • 13
  • 13
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
  • 抗原表位

    • 14
    • 9
    • 8
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-450

    交叉反应

    小鼠, 大鼠

    预测反应

    Human

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human NALP6

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500
    IP(1-2 μg)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

    别名

    NALP6

    背景

    Synonyms: AVR, NAVR, PAN3, NALP6, PYPAF5, CLR11.4, NAVR/AVR, NACHT, LRR and PYD domains-containing protein 6, Angiotensin II/vasopressin receptor, PYRIN-containing APAF1-like protein 5, NLRP6

    Background: May contribute to arginine-vasopressin (AVP)-mediated regulation of renal salt-water balance, glucose and lipid metabolism, apoptosis, and/or cell cycle. Binds arginine-vasopressin but not angiotensin II and acts as an arginine-vasopressin V2 receptor. Plays a role in modulating inflammatory responses in the colon to allow recovery from intestinal epithelial damage and limit tumorigenic potential. Protects against the development of colitis by controlling the composition of the gut microbiota by preventing colonization of the colon by harmful, inflammation-inducing bacteria such as Prevotella species. May mediate activation of CASP1 via ASC, promote activation of NF-kappa-B and stimulate cAMP accumulation (By similarity).

    基因ID

    171389

    UniProt

    P59044

    途径

    Inflammasome
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