CDK2 抗体
Our Local Distributor
北京 101111
Quick Overview for CDK2 抗体 (ABIN2470565)
抗原
See all CDK2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes cdk2, Mr 33kD. Does not cross-react with other cdks.
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纯化方法
- Protein G Column
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免疫原
- CDK2 monoclonal antibody was raised against recombinant CDK2 (Human).
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亚型
- IgG
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应用备注
- CDK2 antibody can be used in immunohistochemistry starting at 10 μg/mL.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05 % sodium azide, before the addition of glycerol to 30 %
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies avoid freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store CDK2 antibody at 4 °C or -20 °C.
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- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
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别名
- CDK2
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背景
- Cyclin-dependent kinase 2 (CDK2), a CDC2/CDK-type protein kinase, regulates cell-cycle transition from G1 to S phase. CDK2 activation requires formation of a heterodimer with cyclin A, D, or E and phosphorylation by CAK. CDK2 inhibition results from association with p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Two alternatively spliced variants and multiple transcription initiation sites have been reported. Inhibition of CDK2 has been suggested to help prevent chemotherapy-induced alopecia in cancer patients.
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基因ID
- 1017
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UniProt
- P24941
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途径
- PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
抗原
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