CDK2 antibody can be used in immunohistochemistry starting at 10 μg/mL.
限制
仅限研究用
状态
Liquid
缓冲液
0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05 % sodium azide, before the addition of glycerol to 30 %
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
As with all antibodies avoid freeze/thaw cycles.
储存条件
4 °C/-20 °C
储存方法
Store CDK2 antibody at 4 °C or -20 °C.
抗原
CDK2
(Cyclin-Dependent Kinase 2 (CDK2))
别名
CDK2
背景
Cyclin-dependent kinase 2 (CDK2), a CDC2/CDK-type protein kinase, regulates cell-cycle transition from G1 to S phase. CDK2 activation requires formation of a heterodimer with cyclin A, D, or E and phosphorylation by CAK. CDK2 inhibition results from association with p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Two alternatively spliced variants and multiple transcription initiation sites have been reported. Inhibition of CDK2 has been suggested to help prevent chemotherapy-induced alopecia in cancer patients.