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CDK2 抗体

This anti-CDK2 antibody is a 小鼠 单克隆 antibody detecting CDK2 in WB, IHC, ELISA 和 IP. Suitable for 人, 小鼠 和 非洲爪蟾.
产品编号 ABIN2470565
发货至: 中国

Quick Overview for CDK2 抗体 (ABIN2470565)

抗原

See all CDK2 抗体
CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

适用

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人, 小鼠, 非洲爪蟾

宿主

  • 212
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小鼠

克隆类型

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单克隆

标记

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This CDK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
  • 特异性

    Recognizes cdk2, Mr 33kD. Does not cross-react with other cdks.

    纯化方法

    Protein G Column

    免疫原

    CDK2 monoclonal antibody was raised against recombinant CDK2 (Human).

    亚型

    IgG
  • 应用备注

    CDK2 antibody can be used in immunohistochemistry starting at 10 μg/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05 % sodium azide, before the addition of glycerol to 30 %

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies avoid freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store CDK2 antibody at 4 °C or -20 °C.
  • 抗原

    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

    别名

    CDK2

    背景

    Cyclin-dependent kinase 2 (CDK2), a CDC2/CDK-type protein kinase, regulates cell-cycle transition from G1 to S phase. CDK2 activation requires formation of a heterodimer with cyclin A, D, or E and phosphorylation by CAK. CDK2 inhibition results from association with p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Two alternatively spliced variants and multiple transcription initiation sites have been reported. Inhibition of CDK2 has been suggested to help prevent chemotherapy-induced alopecia in cancer patients.

    基因ID

    1017

    UniProt

    P24941

    途径

    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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