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PTH1R 抗体 (pThr1)

This anti-PTH1R antibody is a 小鼠 单克隆 antibody detecting PTH1R in WB 和 IHC. Suitable for 人, Cow, Pig, 犬, 猴, 马, Gibbon, Gorilla 和 Orang-Utan.
产品编号 ABIN2470513
发货至: 中国

Quick Overview for PTH1R 抗体 (pThr1) (ABIN2470513)

抗原

See all PTH1R 抗体
PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

适用

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人, Cow, Pig, 犬, 猴, 马, Gibbon, Gorilla, Orang-Utan

宿主

  • 42
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小鼠

克隆类型

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单克隆

标记

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This PTH1R antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    pThr1

    特异性

    Recognizes human PTH/PTHrP receptor, Mr 80kD, and the receptor dimer, Mr 160kD. A faint nonspecific band at 110kD is also detected. This antibody does not detect the PTH2 receptor.

    纯化方法

    Protein G Column

    免疫原

    PTHR1 monoclonal antibody was raised against a synthetic peptide corresponding to aa 146 - 169 of PTHR1 (Human).

    亚型

    IgG1 kappa
  • 应用备注

    PTHR1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 15 μg/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.6, 0.07 % sodium azide, 30 % glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies avoid freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Product should be stored long term (months) at -20 °C and short term (weeks) at 4 °C.
  • 抗原

    PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

    别名

    PTHR1

    背景

    PTHR1, a Parathyroid Hormone Receptor, mediates PTH-dependent regulation of mineral-ion homeostasis. It also mediates the paracrine action of PTHRP in endochondral bone formation. Mutations in this receptor are responsible for disorders of calcium and bone metabolism such as chondrodysplasia, hypercalcemia, and chronic renal failure. Three promoters, P1, P2, and P3, regulate the expression of PTHR.

    基因ID

    5745

    UniProt

    Q03431

    途径

    Regulation of Carbohydrate Metabolic Process
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