PTH1R 抗体 (pThr1)
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Quick Overview for PTH1R 抗体 (pThr1) (ABIN2470513)
抗原
See all PTH1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr1
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特异性
- Recognizes human PTH/PTHrP receptor, Mr 80kD, and the receptor dimer, Mr 160kD. A faint nonspecific band at 110kD is also detected. This antibody does not detect the PTH2 receptor.
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纯化方法
- Protein G Column
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免疫原
- PTHR1 monoclonal antibody was raised against a synthetic peptide corresponding to aa 146 - 169 of PTHR1 (Human).
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亚型
- IgG1 kappa
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应用备注
- PTHR1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 15 μg/mL.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.6, 0.07 % sodium azide, 30 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies avoid freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Product should be stored long term (months) at -20 °C and short term (weeks) at 4 °C.
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- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
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别名
- PTHR1
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背景
- PTHR1, a Parathyroid Hormone Receptor, mediates PTH-dependent regulation of mineral-ion homeostasis. It also mediates the paracrine action of PTHRP in endochondral bone formation. Mutations in this receptor are responsible for disorders of calcium and bone metabolism such as chondrodysplasia, hypercalcemia, and chronic renal failure. Three promoters, P1, P2, and P3, regulate the expression of PTHR.
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基因ID
- 5745
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UniProt
- Q03431
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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