FANCA 抗体 (AA 995-1009)
Quick Overview for FANCA 抗体 (AA 995-1009) (ABIN2470330)
抗原
See all FANCA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 995-1009
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- FANCA antibody was raised against amino acids 995-1009 of FANCA (Human).
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anti-Fanconi Anemia Group A Protein (FANCA) (N-Term) antibody
FANCA 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 1-297) antibodyFANCA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 1121-1170), (pSer1149) antibodyFANCA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 995-1009) antibodyFANCA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (pSer1149) antibodyFANCA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 609-813) antibodyFANCA 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (N-Term) antibodyFANCA 适用: 人 WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 71-120) antibodyFANCA 适用: 人, 猴, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 1-275) antibodyFANCA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) antibodyFANCA 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
- FANCA antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 20 μg/mL.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies avoid freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store FANCA antibody at 4 °C or -20 °C.
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- FANCA (Fanconi Anemia Group A Protein (FANCA))
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别名
- FANCA
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背景
- FANCA (also called Protein FACA or Fanconi anemia group A protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCA may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, and FANCL. The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Variant 1 (isoform a) encodes the longest transcript. Variant 2 (isoform b) contains an alternate exon, which results in an early stop codon, compared to variant 1. Isoform b has a shorter C-terminus when compared to isoform a. Mutations in this gene are the most common cause of Fanconi anemia.
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基因ID
- 2175
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UniProt
- O15360
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途径
- DNA Damage Repair
抗原
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