TGFB1 抗体 (AA 286-293)
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Quick Overview for TGFB1 抗体 (AA 286-293) (ABIN2470323)
抗原
See all TGFB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 286-293
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- TGFB1 antibody was raised against Aa 286-293 (of 390) of full-length (including signal peptide) precursor TGFb protein.
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应用备注
- TGFB1 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 μg/mL.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies avoid freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store TGFB1 antibody at 4 °C or -20 °C.
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- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
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别名
- TGFB1
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背景
- TGF-beta-1 is a multifunctional cytokine that belongs to a superfamily of structurally related regulatory proteins, which includes three mammalian TGF-beta isoforms (TGF-beta-1, -beta-2, and -beta-3), activin/inhibins and bone morphogenetic proteins. The most abundant isoform, TGF-beta-1, is a 25 kDa homodimer composed of two 12.5 kDa subunits joined by disulfide bonds. TGF-beta-1 is a highly conserved molecule - the amino acid sequence between human and mouse differ only by one residue. Although originally defined by its ability to cause anchorage independent cell growth and changes in cell morphology of rat fibroblasts, subsequent research has revealed that TGF-beta is actually a major growth inhibitor for most cell types. It is produced by a wide variety of cell and tissue types during all stages of cell differentiation. TGF-beta-1 sources include platelets, bone and soft tissues such as placenta and kidneys.
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基因ID
- 7040
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UniProt
- P01137
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途径
- EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints
抗原
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