我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

NOTCH2 抗体 (N-Term)

Name: NOTCH2 抗体 (N-Term)
SKU: ABIN2470258
Availability: OutOfStock

This 兔多克隆 antibody specifically detects NOTCH2 in WB, ELISA, IHC 和 IF. It exhibits reactivity toward 人, 犬和 Chimpanzee.

Immunohistochemistry (IHC) image for anti-Notch 2 (NOTCH2) (N-Term) antibody (ABIN2470258) (NOTCH2 抗体 (N-Term))

IHC

1 image

产品编号 ABIN2470258

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for NOTCH2 抗体 (N-Term) (ABIN2470258)

抗原

See all NOTCH2 抗体

NOTCH2 (Notch 2 (NOTCH2))

适用

人, 犬, Chimpanzee

宿主

兔

克隆类型

多克隆

标记

This NOTCH2 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Discover our top product NOTCH2 Primary Antibody

抗原表位
16

15

5

5

5

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term

纯化方法

Sterile Filtration

免疫原

NOTCH2 antibody was raised against amino acid residues 2396 - 2409 of NOTCH2. A residue of cysteine was added to the amino terminal end to facilitate coupling (Human).
anti-Notch 2 (NOTCH2) antibody
NOTCH2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Notch 2 (NOTCH2) (Asp1733), (cleaved) antibody
NOTCH2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Notch 2 (NOTCH2) (C-Term) antibody
NOTCH2 适用: 人, 小鼠 WB, ChIP-seq 宿主: 兔 Polyclonal unconjugated

anti-Notch 2 (NOTCH2) (AA 1501-1700) antibody
NOTCH2 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Notch 2 (NOTCH2) (cleaved), (Internal Region) antibody
NOTCH2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Notch 2 (NOTCH2) (AA 2242-2471) antibody
NOTCH2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Notch 2 (NOTCH2) (AA 59-250) antibody
NOTCH2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Notch 2 (NOTCH2) (AA 2251-2466) antibody
NOTCH2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Notch 2 (NOTCH2) (cleaved), (Internal Region) antibody
NOTCH2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Notch 2 (NOTCH2) antibody
NOTCH2 适用: 小鼠, 大鼠 FACS 宿主: 仓鼠 Monoclonal HMN2-35 unconjugated

应用备注

NOTCH2 antibody can be used in Western Blot starting at 0.5 - 4 μg/mL, and immunohistochemistry starting at 5 μg/mL.

限制

仅限研究用
状态

Liquid

缓冲液

0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.1 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

As with all antibodies avoid freeze/thaw cycles.

储存条件

4 °C/-20 °C

储存方法

Store NOTCH2 antibody at 4 °C or -20 °C.
抗原

NOTCH2 (Notch 2 (NOTCH2))

别名

NOTCH2

背景

Notch is synthesized in the endoplasmic reticulum as an inactive form which is proteolytically cleaved by a furin-like convertase (S1 cleavage) in the trans-golgi network before it reaches the plasma membrane to yield an active, ligand-accessible form. Cleavage results in a C-terminal fragment N(TM) and a N-terminal fragment N(EC). Following ligand binding, it is cleaved (S2 cleavage) by TNF-alpha converting enzyme (TACE) to yield a membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). This fragment is then cleaved by presenilin-dependent gamma-secretase (S3 cleavage) to release the intracellular domain (NICD) from the membrane. Notch functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBP-J kappa and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.

基因ID

4853

UniProt

Q04721

途径

Notch Signaling, Stem Cell Maintenance