Integrin beta 2 抗体 (AA 534-546)
Quick Overview for Integrin beta 2 抗体 (AA 534-546) (ABIN2469881)
抗原
See all Integrin beta 2 (ITGB2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 534-546
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特异性
- Recongizes an epitope involving residues 534-546 in cysteine-rich repeat 3 of the CD18 antigen (integrin beta2 subunit, beta2 integrin).
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纯化方法
- Protein A Column
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免疫原
- Integrin beta 2 monoclonal antibody was raised against Integrin beta 2 (Human).
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亚型
- IgG1
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应用备注
- Integrin beta 2 antibody can be used in ELISA starting at 1:100000, Western Blot starting at 1:1000 - 1:10000, and immunohistochemistry starting at 5 μg/mL.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, 15 mM sodium azide, approx., pH 7.4.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies avoid freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Integrin beta 2 antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.
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- Integrin beta 2 (ITGB2)
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别名
- Integrin beta 2
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背景
- CD18 is a 90-95 kDa type I transmembrane protein expressed on all leukocytes. The ITGB2 protein product is the integrin beta chain beta 2. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
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基因ID
- 3689
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UniProt
- P05107
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途径
- NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
抗原
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