Insulin Receptor 抗体 (Internal Region)
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- 抗原 See all Insulin Receptor (INSR) 抗体
- Insulin Receptor (INSR)
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抗原表位
- Internal Region
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适用
- 人, 猴, Gorilla, Gibbon
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Insulin Receptor antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 特异性
- BLAST analysis of the peptide immunogen showed no homology with other human proteins, except JARID2 (69 % ).
- 纯化方法
- Immunoaffinity Chromatography
- 免疫原
- Insulin Receptor antibody was raised against a peptide located near the internal domain of Insulin Receptor (Human).
- Top Product
- Discover our top product INSR Primary Antibody
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- 应用备注
- Insulin Receptor antibody can be used in ELISA starting at 1:10000, and immunohistochemistry starting at 1:200 - 1:400.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, 0.1 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies avoid freeze/thaw cycles.
- 储存条件
- 4 °C/-80 °C
- 储存方法
- Insulin Receptor antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
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- 抗原
- Insulin Receptor (INSR)
- 别名
- Insulin Receptor (INSR 产品)
- 别名
- CD220 antibody, HHF5 antibody, 4932439J01Rik antibody, D630014A15Rik antibody, IR antibody, IR-A antibody, IR-B antibody, 18402 antibody, CG18402 antibody, DIHR antibody, DILR antibody, DIR antibody, DIRH antibody, DIRbeta antibody, DInR antibody, DInr antibody, Dir-a antibody, Dir-b antibody, Dmel\\CG18402 antibody, INR antibody, INS antibody, Inr antibody, Inr-alpha antibody, Inr-beta antibody, InsR antibody, dINR antibody, dIR antibody, dIRH antibody, dInR antibody, dInr antibody, dInsR antibody, dinr antibody, dir antibody, er10 antibody, inr antibody, insulin/insulin-like growth factor receptor antibody, l(3)05545 antibody, l(3)93Dj antibody, l(3)er10 antibody, lnR antibody, ir-A antibody, CTK-1 antibody, ir antibody, INSR antibody, NV14476 antibody, cd220 antibody, hhf5 antibody, insulin receptor antibody, Insulin-like receptor antibody, insulin receptor L homeolog antibody, INSR antibody, Insr antibody, InR antibody, LOC100122567 antibody, LOC100451802 antibody, insr.L antibody
- 背景
- INSR is an insulin receptor type protein kinase. Binding of insulin to INSR stimulates glucose uptake. Two insulin receptor mRNA transcripts resulting from alternative splicing of exon 11 in the receptor gene are expressed in a highly regulated tissue-specific fashion. Mutations in the INSR gene contribute to diseases, including of various forms of insulin resistance, insulin-resistant diabetes mellitus, noninsulin-dependent diabetes mellitus (NIDDM), Rabson-Mendenhall syndrome and Leprechaunism (Donohue Syndrome).
- 基因ID
- 3643
- UniProt
- P06213
- 途径
- NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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