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Insulin Receptor 抗体 (Internal Region)

This anti-Insulin Receptor antibody is a 兔 多克隆 antibody detecting Insulin Receptor in IHC. Suitable for 人, 猴, Gibbon 和 Gorilla.
产品编号 ABIN2469537
发货至: 中国

Quick Overview for Insulin Receptor 抗体 (Internal Region) (ABIN2469537)

抗原

See all Insulin Receptor (INSR) 抗体
Insulin Receptor (INSR)

适用

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人, 猴, Gibbon, Gorilla

宿主

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克隆类型

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多克隆

标记

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This Insulin Receptor antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    Internal Region

    特异性

    BLAST analysis of the peptide immunogen showed no homology with other human proteins, except JARID2 (69 % ).

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    Insulin Receptor antibody was raised against a peptide located near the internal domain of Insulin Receptor (Human).
  • 应用备注

    Insulin Receptor antibody can be used in ELISA starting at 1:10000, and immunohistochemistry starting at 1:200 - 1:400.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, 0.1 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies avoid freeze/thaw cycles.

    储存条件

    4 °C/-80 °C

    储存方法

    Insulin Receptor antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
  • 抗原

    Insulin Receptor (INSR)

    别名

    Insulin Receptor

    背景

    INSR is an insulin receptor type protein kinase. Binding of insulin to INSR stimulates glucose uptake. Two insulin receptor mRNA transcripts resulting from alternative splicing of exon 11 in the receptor gene are expressed in a highly regulated tissue-specific fashion. Mutations in the INSR gene contribute to diseases, including of various forms of insulin resistance, insulin-resistant diabetes mellitus, noninsulin-dependent diabetes mellitus (NIDDM), Rabson-Mendenhall syndrome and Leprechaunism (Donohue Syndrome).

    基因ID

    3643

    UniProt

    P06213

    途径

    NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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