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MST1R 抗体 (Internal Region)

MST1R 适用: 人, 猴, Bat, Gorilla IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2469460
发货至: 中国
  • 抗原 See all MST1R 抗体
    MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
    抗原表位
    • 41
    • 21
    • 14
    • 12
    • 11
    • 11
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 98
    • 62
    • 41
    • 5
    • 1
    • 1
    人, 猴, Bat, Gorilla
    宿主
    • 109
    • 3
    • 2
    克隆类型
    • 103
    • 11
    多克隆
    标记
    • 38
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This MST1R antibody is un-conjugated
    应用范围
    • 82
    • 36
    • 23
    • 20
    • 17
    • 15
    • 15
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    特异性
    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    MST1R antibody was raised against a peptide located near the internal domain of MST1R (Human).
    Top Product
    Discover our top product MST1R Primary Antibody
  • 应用备注
    MST1R antibody can be used in immunohistochemistry starting at 20 μg/mL, and immunofluorescence.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, 0.1 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    As with all antibodies avoid freeze/thaw cycles.
    储存条件
    4 °C/-80 °C
    储存方法
    MST1R antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
  • 抗原
    MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
    别名
    MST1R (MST1R 产品)
    别名
    CD136 antibody, CDw136 antibody, PTK8 antibody, RON antibody, Fv-2 antibody, Fv2 antibody, Ron antibody, STK antibody, Cdw136 antibody, Ptk8 antibody, Stk antibody, macrophage stimulating 1 receptor antibody, macrophage stimulating 1 receptor (c-met-related tyrosine kinase) antibody, MST1R antibody, Mst1r antibody
    背景
    MST1R/Ron, a HGF Receptor/MET-type protein kinase, mediates the biological activities of macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival. The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits. Ligand binding results in tyrosine phosphorylation of the beta chain. In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period. The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers.
    基因ID
    4486
    UniProt
    Q04912
    途径
    RTK signaling
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