EPH Receptor A4 抗体 (C-Term)
Quick Overview for EPH Receptor A4 抗体 (C-Term) (ABIN2469317)
抗原
See all EPH Receptor A4 (EPHA4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- EPHA4 antibody was raised against a peptide located in the C-Terminal domain of EPHA4 (Human).
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应用备注
- EPHA4 antibody can be used in immunohistochemistry starting at 7.3 μg/mL.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, 0.1 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies avoid freeze/thaw cycles.
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储存条件
- 4 °C/-80 °C
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储存方法
- EPHA4 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
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- EPH Receptor A4 (EPHA4)
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别名
- EPHA4
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背景
- Nak1, a NR4 Nerve Growth Factor-Like receptor, has been shown to affect the hypothalamic-pituitary axis, neuronal differentiation, neuroendocrine regulation of adrenocortical function, and T-cell apoptosis. Nak1 also is known as nuclear receptor Tr3 and is similar to mouse Nur77 and rat NGFI-B. It is encoded by one of the immediate early genes (IEG) in response to nerve growth factor and other serum growth factors. Nak1 can bind to DNA as a monomer, homodimer, or heterodimer (with retinoid X receptors). Nak1 has been shown to inhibit vascular lesion formation and could serve as a novel target in the treatment of vascular diseases.
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基因ID
- 2043
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UniProt
- P54764
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途径
- RTK signaling
抗原
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