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TRIM5 抗体 (truncated)

TRIM5 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 3B11H2 unconjugated
产品编号 ABIN2464117
发货至: 中国
  • 抗原 See all TRIM5 抗体
    TRIM5 (Tripartite Motif Containing 5 (TRIM5))
    抗原表位
    • 13
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    truncated
    适用
    • 45
    • 4
    • 4
    • 1
    • 1
    宿主
    • 40
    • 3
    • 2
    小鼠
    克隆类型
    • 41
    • 3
    单克隆
    标记
    • 31
    • 4
    • 3
    • 3
    • 2
    • 2
    This TRIM5 antibody is un-conjugated
    应用范围
    • 39
    • 28
    • 10
    • 9
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    免疫原
    Ni-NTA purified truncated recombinant human trim5 alpha expressed in E. Coli strain BL21 (DE3).
    克隆位点
    3B11H2
    亚型
    IgG1
    Top Product
    Discover our top product TRIM5 Primary Antibody
  • 应用备注
    Western Blot:Dilution 1:1,000 - 1:5,000
    IHC(P):Dilution 1:100 - 1:400
    IHC(F):Dilution 1:200 - 1:400
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    储存条件
    -20 °C
    储存方法
    Trim5? monoclonal antibody can be stored at -20 °C, stable for one year.
  • 抗原
    TRIM5 (Tripartite Motif Containing 5 (TRIM5))
    别名
    Trim5a (TRIM5 产品)
    别名
    TRIM5 antibody, RNF88 antibody, TRIM5alpha antibody, EG667823 antibody, Gm8833 antibody, RGD1304579 antibody, tripartite motif containing 5 antibody, tripartite motif-containing 5 antibody, TRIM5 antibody, Trim5 antibody
    背景
    TRIM5-alpha is a protein that is found in the cells of many mammals and fends of various retrovirus infections. It protects monkeys from infection with HIV-1, and humans from infection with some other viruses. If a retrovirus has entered a cell, it needs to shed its capsid in order to reversely transcribe its genes, so that they can be expressed by the host cell. It is believed that TRIM5alpha, which is present in the cytoplasm, somehow recognizes the capsid and blocks its shedding, thereby stopping the virus in its tracks. It thus represents an intracellular defense completely separate from the rest of the body's immune system.
    基因ID
    85364
    UniProt
    Q9NUD5
    途径
    Activation of Innate immune Response
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