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TRIM5 抗体 (truncated)

This anti-TRIM5 antibody is a 小鼠 单克隆 antibody detecting TRIM5 in WB 和 IHC. Suitable for 人.
产品编号 ABIN2464117
发货至: 中国

Quick Overview for TRIM5 抗体 (truncated) (ABIN2464117)

抗原

See all TRIM5 抗体
TRIM5 (Tripartite Motif Containing 5 (TRIM5))

适用

  • 39
  • 3
  • 2
  • 1
  • 1

宿主

  • 35
  • 3
  • 1
小鼠

克隆类型

  • 36
  • 3
单克隆

标记

  • 30
  • 3
  • 2
  • 2
  • 1
  • 1
This TRIM5 antibody is un-conjugated

应用范围

  • 33
  • 23
  • 11
  • 8
  • 4
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

3B11H2
  • 抗原表位

    • 7
    • 7
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    truncated

    免疫原

    Ni-NTA purified truncated recombinant human trim5 alpha expressed in E. Coli strain BL21 (DE3).

    亚型

    IgG1
  • 应用备注

    Western Blot:Dilution 1:1,000 - 1:5,000
    IHC(P):Dilution 1:100 - 1:400
    IHC(F):Dilution 1:200 - 1:400
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

    储存条件

    -20 °C

    储存方法

    Trim5? monoclonal antibody can be stored at -20 °C, stable for one year.
  • 抗原

    TRIM5 (Tripartite Motif Containing 5 (TRIM5))

    别名

    Trim5a

    背景

    TRIM5-alpha is a protein that is found in the cells of many mammals and fends of various retrovirus infections. It protects monkeys from infection with HIV-1, and humans from infection with some other viruses. If a retrovirus has entered a cell, it needs to shed its capsid in order to reversely transcribe its genes, so that they can be expressed by the host cell. It is believed that TRIM5alpha, which is present in the cytoplasm, somehow recognizes the capsid and blocks its shedding, thereby stopping the virus in its tracks. It thus represents an intracellular defense completely separate from the rest of the body's immune system.

    基因ID

    85364

    UniProt

    Q9NUD5

    途径

    Activation of Innate immune Response
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