MERTK 抗体 (full length)
Our Local Distributor
北京 101111
Quick Overview for MERTK 抗体 (full length) (ABIN2464082)
抗原
See all MERTK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- full length
-
免疫原
- Ni-NTA purified full-length recombinant MER-His expressed in E. Coli strain BL21 (DE3).
-
亚型
- IgG1
-
-
-
-
应用备注
-
Western Blot:1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
储存条件
- -20 °C
-
储存方法
- MER monoclonal antibody can be stored at -20 °C, stable for one year.
-
-
- MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
-
别名
- MER
-
背景
- MER (c-mer proto-oncogene tyrosine kinase) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. MER has been identified as a tyrosine kinase potentially involved in the development of glioblastomas. It is expressed at highest levels in ovary, prostate, lung and kidney. Gas6, a growth arrest specific gene, and the related anticoagulation factor Protein S have been identified as ligands for the UFO family of receptors. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
-
基因ID
- 10461
-
UniProt
- Q12866
-
途径
- RTK signaling
抗原
-