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MERTK 抗体 (full length)

This anti-MERTK antibody is a 小鼠 单克隆 antibody detecting MERTK in WB 和 ELISA. Suitable for 人.
产品编号 ABIN2464082
发货至: 中国

Quick Overview for MERTK 抗体 (full length) (ABIN2464082)

抗原

See all MERTK 抗体
MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

适用

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宿主

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小鼠

克隆类型

  • 60
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单克隆

标记

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This MERTK antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

7E5G1
  • 抗原表位

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    full length

    免疫原

    Ni-NTA purified full-length recombinant MER-His expressed in E. Coli strain BL21 (DE3).

    亚型

    IgG1
  • 应用备注

    Western Blot:1:500 - 1:2,000
    ELISA:Propose dilution 1:10,000.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

    储存条件

    -20 °C

    储存方法

    MER monoclonal antibody can be stored at -20 °C, stable for one year.
  • 抗原

    MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

    别名

    MER

    背景

    MER (c-mer proto-oncogene tyrosine kinase) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. MER has been identified as a tyrosine kinase potentially involved in the development of glioblastomas. It is expressed at highest levels in ovary, prostate, lung and kidney. Gas6, a growth arrest specific gene, and the related anticoagulation factor Protein S have been identified as ligands for the UFO family of receptors. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

    基因ID

    10461

    UniProt

    Q12866

    途径

    RTK signaling
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