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PARL 抗体

PARL 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2463992
发货至: 中国
  • 抗原 See all PARL 抗体
    PARL (Presenilin Associated, Rhomboid-Like (PARL))
    适用
    • 20
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 16
    • 3
    • 2
    克隆类型
    • 18
    • 3
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PARL antibody is un-conjugated
    应用范围
    • 11
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PARL.
    Top Product
    Discover our top product PARL Primary Antibody
  • 应用备注
    PARL antibody can be used for detection of PARL by ELISA at 1:312500. PARL antibody can be used for detection of PARL by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store PARL antibody at -20 °C.
  • 抗原
    PARL (Presenilin Associated, Rhomboid-Like (PARL))
    别名
    PARL (PARL 产品)
    别名
    PSARL antibody, PSARL1 antibody, PSENIP2 antibody, RHBDS1 antibody, D16Ertd607e antibody, PRO2207 antibody, Psarl antibody, parl antibody, zgc:112986 antibody, presenilin associated rhomboid like antibody, presenilin associated, rhomboid-like antibody, presenilin associated, rhomboid-like a antibody, PARL antibody, Parl antibody, parla antibody
    背景
    PARL is a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. PARL may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in its gene has been associated with increased risk for type 2 diabetes.This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
    分子量
    36 kDa, 42 kDa
    基因ID
    55486
    NCBI登录号
    NP_001032728
    途径
    Autophagy
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