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PARL 抗体

This anti-PARL antibody (ABIN2463992) is a Rabbit Polyclonal antibody detecting PARL in WB, ELISA, IHC. Suitable for Human, Mouse, Rat, Dog.
产品编号 ABIN2463992
发货至: 中国

Quick Overview for PARL 抗体 (ABIN2463992)

抗原

See all PARL 抗体
PARL (Presenilin Associated, Rhomboid-Like (PARL))

适用

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人, 小鼠, 大鼠, 犬

宿主

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克隆类型

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多克隆

标记

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This PARL antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PARL.
  • 应用备注

    PARL antibody can be used for detection of PARL by ELISA at 1:312500. PARL antibody can be used for detection of PARL by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store PARL antibody at -20 °C.
  • 抗原

    PARL (Presenilin Associated, Rhomboid-Like (PARL))

    别名

    PARL

    背景

    PARL is a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. PARL may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in its gene has been associated with increased risk for type 2 diabetes.This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.

    分子量

    36 kDa, 42 kDa

    基因ID

    55486

    NCBI登录号

    NP_001032728

    途径

    Autophagy
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