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MUC1 抗体

This anti-MUC1 antibody is a 兔 多克隆 antibody detecting MUC1 in IHC, WB 和 ELISA. Suitable for 人, 小鼠 和 犬.
产品编号 ABIN2462410
发货至: 中国

Quick Overview for MUC1 抗体 (ABIN2462410)

抗原

See all MUC1 抗体
MUC1 (Mucin 1 (MUC1))

适用

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人, 小鼠, 犬

宿主

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克隆类型

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多克隆

标记

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This MUC1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MUC1.
  • 应用备注

    MUC1 antibody can be used for detection of MUC1 by ELISA at 1:312500. MUC1 antibody can be used for detection of MUC1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store MUC1 antibody at -20 °C.
  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    MUC1

    背景

    MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.

    分子量

    22 kDa, 28 kDa, 28 kDa, 16 kDa, 17 kDa, 30 kDa

    基因ID

    4582

    NCBI登录号

    NP_001037855

    UniProt

    Q7Z552

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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