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MTA1 抗体

This anti-MTA1 antibody is a 兔 多克隆 antibody detecting MTA1 in WB 和 ELISA. Suitable for 人, 小鼠, 大鼠, 犬 和 斑马鱼.
产品编号 ABIN2461592
发货至: 中国

Quick Overview for MTA1 抗体 (ABIN2461592)

抗原

See all MTA1 抗体
MTA1 (Metastasis Associated 1 (MTA1))

适用

  • 49
  • 27
  • 21
  • 7
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  • 2
  • 2
  • 2
  • 1
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  • 1
人, 小鼠, 大鼠, 犬, 斑马鱼

宿主

  • 44
  • 7
  • 1

克隆类型

  • 45
  • 7
多克隆

标记

  • 39
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MTA1 antibody is un-conjugated

应用范围

  • 40
  • 21
  • 14
  • 10
  • 9
  • 7
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by protein A chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MTA1.
  • 应用备注

    MTA1 antibody can be used for detection of MTA1 by ELISA at 1:312500. MTA1 antibody can be used for detection of MTA1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store MTA1 antibody at -20 °C.
  • 抗原

    MTA1 (Metastasis Associated 1 (MTA1))

    别名

    MTA1

    背景

    MTA1 encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. MTA1 was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling.

    分子量

    47 kDa, 81 kDa, 59 kDa

    基因ID

    9112

    途径

    Chromatin Binding
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