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ATG4B 抗体

This anti-ATG4B antibody is a 兔 多克隆 antibody detecting ATG4B in WB 和 ELISA. Suitable for 人, 小鼠, 大鼠 和 犬.
产品编号 ABIN2460952
发货至: 中国

Quick Overview for ATG4B 抗体 (ABIN2460952)

抗原

See all ATG4B 抗体
ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

适用

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人, 小鼠, 大鼠, 犬

宿主

  • 104
  • 5

克隆类型

  • 101
  • 8
多克隆

标记

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  • 7
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  • 2
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  • 1
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  • 1
  • 1
  • 1
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  • 1
  • 1
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This ATG4B antibody is un-conjugated

应用范围

  • 83
  • 35
  • 25
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  • 11
  • 7
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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by protein A chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ATG4B.
  • 应用备注

    ATG4B antibody can be used for detection of ATG4B by ELISA at 1:12500. ATG4B antibody can be used for detection of ATG4B by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store ATG4B antibody at -20 °C.
  • 抗原

    ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

    别名

    ATG4B

    背景

    Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. APG4B encodes a member of the autophagin protein family and is also designated as a member of the C-54 family of cysteine proteases.Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    分子量

    44 kDa, 36 kDa, 55 kDa, 54 kDa

    基因ID

    23192

    NCBI登录号

    NP_037457

    UniProt

    Q9Y4P1

    途径

    Autophagy
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