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- 抗原 See all INSIG1 抗体
- INSIG1 (Insulin Induced Gene 1 (INSIG1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This INSIG1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Antibody is purified by peptide affinity chromatography method.
- 免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human INSIG1.
- Top Product
- Discover our top product INSIG1 Primary Antibody
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anti-Insulin Induced Gene 1 (INSIG1) (AA 1-87) antibody
INSIG1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Internal Region) antibodyINSIG1 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 63-112) antibodyINSIG1 适用: 人, 小鼠, 大鼠, 马, 兔, Cow, 山羊, 豚鼠, 犬, Pig, 猴, Hamster, 非洲爪蟾, Bat, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 1-100) antibodyINSIG1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 36-63), (N-Term) antibodyINSIG1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21689 unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibodyINSIG1 适用: 人, 小鼠, 大鼠, 马, 兔, Cow, 山羊, 豚鼠, 绵羊, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 71-120) antibodyINSIG1 适用: 人, 小鼠, 大鼠, 马, 兔, Cow, 山羊, 绵羊, Pig, Hamster, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (C-Term) antibodyINSIG1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (C-Term) antibodyINSIG1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibodyINSIG1 适用: 人, 小鼠, 大鼠, 马, 兔, Cow, 山羊, 豚鼠, 绵羊, 犬, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- INSIG1 antibody can be used for detection of INSIG1 by ELISA at 1:1562500. INSIG1 antibody can be used for detection of INSIG1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- 注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store INSIG1 antibody at -20 °C.
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- 抗原
- INSIG1 (Insulin Induced Gene 1 (INSIG1))
- 别名
- INSIG1 (INSIG1 产品)
- 别名
- cl-6 antibody, cl6 antibody, CL-6 antibody, CL6 antibody, fb55a03 antibody, fi35b10 antibody, wu:fb55a03 antibody, wu:fi35b10 antibody, zgc:55439 antibody, 1810013C12Rik antibody, Insig-1 antibody, INSIG-1 antibody, insulin induced gene 1 antibody, insulin induced gene 1 L homeolog antibody, INSIG1 antibody, insig1 antibody, insig1.L antibody, Insig1 antibody
- 背景
- Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. INSIG1 is an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. INSIG1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins.The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
- 分子量
- 25 kDa
- 基因ID
- 51141
- NCBI登录号
- NP_057217
- UniProt
- Q9Y5U4
- 途径
- ER-Nucleus Signaling
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